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EPISKIN, world leader in tissue engineering, is partnering with the cosmetic, pharmaceutical and chemical industries to develop relevant and reliable safety and efficacy tests for decision-making during the research and development phases. Some screening tests are referenced and validated as alternatives to animal use; others are in the process of validation. EPISKIN has been positively reviewed by the ESAC for the validation of the SkinEhic HCE in the context of alternative to animal testing within the perspective of the European Cosmetics Directive and inserted in the OECD TG 492 guideline. This OECD guideline concretizes the official recognition of the SkinEthic HCE method. EPISKIN is also involved in a Round Robin Studay for Medical Devices for skin irritation in the 10993 ISO Norm.


  • 3D SKIN

    - RHE (Reconstructed Human Epidermis) - EpiSkin (Reconstructed Human Epidermis) - HCE (Human Corneal Epithelium) - RHPE (Reconstructed Human Pigm...

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  • Contact Information


    4, rue Alexander Fleming LYON Cedex 07 69366 France
    Tel:  +33 4 37 28 22 00
    Fax:  +33 4 37 28 22 01


  1. Company Activity
    Testing & Research
  2. Looking for Distributors
    (Not looking for a distributor)
  3. Company Size 101-500

Company White Papers

  • TG 492 OECD guideline for the testing...

    TG 492 Guideline for eye assessment using SkinEthic HCE is now officially available on the OECD website. This protocol validated by EURL ECVAM and rec...

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