Cosmeceutical development - An in-silico approach

Cosmeceutical development - An in-silico approach

20 Jun 2017, 16:00 - 16:45

Marketing Trends & Regulations Theatre


An in-silico approach to predicting toxicity and efficacy has become increasingly important, in both regulatory aspects (e.g. EU REACH and the Cosmetics Regulation) and new ingredient screening.

The main goal of in-silico approaches is to predict the toxicity and efficacy of chemicals or drugs with computational modeling, QSARs, and algorithms with toxicological data and information.

In-silico evaluation is viewed as one of the alternatives to animal testing. It is a broad term that is taken to indicate a variety of computational techniques which relate the structure of a chemical to its toxicity or efficacy.

The purpose of an in-silico approach is to provide techniques to retrieve relevant data and/or make predictions regarding the fate and effects of chemicals. In this sense, the term ‘in-silico’ is used in the same manner as in-vitro and in-vivo, with ‘silico’ relating to the computational nature of the work.

There are, obviously, many advantages to in-silico techniques, including their cost-effectiveness, speed compared with traditional testing, and reduction in animal use.



  • Seokjoo Yoon


    Director, Department of Predictive Toxicology

    Korea Institute of Toxicology

    Dr. Yoon received his Ph.D. from Hokkaido University, Japan in Toxicology. After receiving his Ph.D., he moved to the Division of Molecular...

We use cookies to operate this website and to improve its usability. Full details of what cookies are, why we use them and how you can manage them can be found by reading our Privacy & Cookies page. Please note that by using this site you are consenting to the use of cookies.